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About PGT-A
About PGT-A
About our service
The test is performed using approximately 5-10 cells obtained from a biopsy of the trophic ectoderm (TE) of a blastocyst on thet fifth day afterfertilization.
The whole genome of the cell-derived human DNA is amplified and the increase or decrease in chromosome number is examined based on diploid/euploid chromosomes, which have two copies each.
Depending on the specimen, mosaic aneuploidymay be detectedMosaic aneuploidy is a condition in which cells without chromosomal aneuploidy and cells with chromosomal aneuploidy are mixed in the analyzed fetal tissues. Mosaic aneuploidy may disappear as the fetus develops, but there is a risk that it may cause infertility, repeated implantation failure, or the birth of a child with birth defects, mental retardation or developmental disabilities.
Features
・Specimens are transported by a specialized specimen transport company.
・Includes multiplicity analysis as the standard.
・KAT-Score, a comprehensive evaluation of the degree of mosaicism, is indicated.
・Notation of the embryo score, which is a combination of two evaluations; PGT-A results and the embryo grade
If you are interested in our test, please contact our inquiry desk(info@varinos.com).
※This service is for research use only.
Flow of PGT-A
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01
Before making a request
Please contact our sales representative.
Our sales representative will explain the contract, inspection request, and additional necessary paperwork. -
02
Order a test kit
Please fill out the "PGT-A Kit Order Form" and fax it to us.
The kit will be sent by frozen delivery.
The kit includes a test request form, 0.2mL PCR tubes, 1% PVP-PBS solution (3 tubes), TubingBuffer (3 tubes), 96-well box and 96-well boxlabel, and specimen barcode labels(15 labels). -
03
Specimen collection and packaging
Please collect the specimen and package it according to our instructions.
Please fill out the "Test Request Form" with the specimen information. -
04
Delivery of specimens
Please fill out the "Specimen Collection Request Form" and fax it to us.
A representative from our affiliated specimen transport company will visit you to collect your specimen. -
05
Report of test results
We will perform DNA analysis and secondary data analysis using a next-generation sequencer at our laboratory, and return the test result report to you.
The report will be sent to you within 10 business days from the date we receive your specimen. (Excluding Saturdays, Sundays, and national holidays)
Please note that the delivery date may be delayed depending on the progress of the Japanese Society of Obstetrics and Gynecology's Committee for Evaluation of Analysis Results. Please be aware of this in advance.